Can the KTM 1290 Super Adventure S be used for long-distance touring?

Many adventure bike riders, especially those planning a long road trip or a transcontinental ride, will prioritize long-distance comfort. The KTM 1290 Super Adventure S is brimming with features designed to improve rider comfort with an adjustable windscreen, cruise control, and different riding modes. But some riders wonder if it's too much sporty DNA and too much power for all-day comfort. Potential buyers have concerns about seat comfort, vibration levels, and wind protection. In this question, we want to get a grip on the real-world experiences of riders who have ridden their 1290 Super Adventure S on long trips and how they feel about this in terms of fatigue, ergonomics, and touring suitability when compared to more traditional touring-oriented adventure bikes.